States United States stationed in downtown business district on August 1 Square test business - GOME Electrical Appliances, Haier, Hisense - HC networ
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The Last Checkpoint to T Cell Fate
A research team in Japan has linked a developmental checkpoint in the differentiation of hematopoietic progenitors into specific T cell lineages to the activity of a single gene encoding a transcription factor. Reported in Science this week, the discovery lends support to a new model for the development of blood cells lineages.

New Research Uncovers Elusive Target of Antifungal Agent
A research team in Japan has uncovered the mechanism underlying the antifungal activity of theonellamide (TNM), a bioactive compound found in a species of marine sponge. The finding, reported in Nature Chemical Biology, provides new insights toward the development of antifungal drugs, with broader applications to drug analysis in areas such as cancer research.